Molecule Maker Lab Institute

AlphaSynthesis

Tool

Somn

Initial Release

Welcome to our initial release

We welcome your suggestions and feedback. New features and improvements will be released over the coming weeks.

Predicting substrate-adaptive conditions for C–N couplings

Welcome to Somn!

We’re trained a model called Somn for predicting substrate-adaptive conditions for C-N couplings. Somn is your experimental design assistant: you provide reactant pairs and Somn will make yield percent predictions for a variety of reaction conditions (catalysts, solvents, and bases), which you can use to inform your own synthesis planning.
Learn more about how Somn works below and get started using the tool today.

Somn Workflow

Request Configuration
  • Input an aryl halide / amine reactant pair for reaction condition prediction (catalysts, solvents, andbases)
Analysis
  • Somn analyzes your reactant pair input to make yield percentage predictions across a variety of reaction conditions
  • Optionally submit an email address to receive a notification when your results are ready
Model Results
  • Access model outputs such as yield percentage predictions and reaction conditions for your input reactants